Probiotics and human microbiota - Probiotici e microbiota umano


Address: Plesso Chimico Parco area delle Scienze 17A, 43123 Parma 
Professors and researchers: 
Prof.ssa Francesca Turroni - 
Department of Chemistry, Life Sciences and Environmental Sustainability



Research topics

Research topics are related to different –omics approaches (genomics and functional genomics) of intestinal bacteria, metagenomics and microbial genomics of bifidobacteria and probiotic bacteria.



1.     Milani C., Fontana F., Alessandri G., Mancabelli L., Lugli GA., Longhi G., Anzalone R., Viappiani A., Duranti S., Turroni F., Ossiprandi MC., van Sinderen D., Ventura M. (2020) Ecology of Lactobacilli Present in Italian Cheeses Produced from Raw Milk. Applied and Environmental Microbiology. 86 (12).

2.     Milani, C., Duranti, S., Napoli, S., Alessandri, G., Mancabelli, L., Anzalone, R., Longhi, G., Viappiani, A., Mangifesta, M., Lugli, G.A., Bernasconi, S., Ossiprandi, M.C., van Sinderen, D., Ventura, M., and Turroni F. (2019). Colonization of the human gut by bovine bacteria present in Parmesan cheese. Nature Comm. 10 (1), 1286.

3.     Mangifesta, M., Mancabelli, L., Milani, C., Gaiani, F., de'Angelis, N., de’Angelis, G.L., van Sinderen, D., Ventura, M., and Turroni, F. (2018). Mucosal microbiota of intestinal polyps reveals putative biomarkers of colorectal cancer. Scientific reports, 8(1), 1-9.  

4.     Turroni F., Milani C, Duranti S, Mahony J, van Sinderen D, Ventura M. (2017) Glycan Utilization and Cross-Feeding Activities by Bifidobacteria. Trends Microbiol. 4:339-350.

5.     Milani, C., Mangifesta, M., Mancabelli, L., Lugli, G., Mancino, W., Viappiani, A., Faccini, A., van Sinderen, D., Ventura, M., and Turroni, F.  (2017). The sortase-dependent fimbriome of the genus Bifidobacterium: extracellular structures with potential to modulate microbe-host dialogue. Appl. Environ. Microbiol. 83(19)

6.     Mancino, W., Duranti, S., Mancabelli, L., Longhi, G., Anzalone, R., Milani, C., Lugli, G.A., Carnevali, L., Statello, R., Sgoifo, A., van Sinderen, D., Ventura, M., and Turroni, F.  (2019). Bifidobacterial transfer from mother to child as examined by an animal model. Microorganisms 7(9), 293.

7.     Lugli, G.A., Mancino, W., Milani, C., Duranti, S., Mancabelli, L., Napoli, S., Mangifesta, M., Viappiani, A., Anzalone, R., Longhi, G., van Sinderen, D., Ventura, M., and Turroni, F. (2019). Dissecting the evolutionary development of the Bifidobacterium animalis species through comparative genomics analyses. Appl. Environ. Microbiol. 85 (7).

8.     Ferrario C, Statello R, Carnevali L, Mancabelli L, Milani C, Mangifesta M, Duranti S, Lugli GA, Jimenez B, Lodge S, Viappiani A, Alessandri G, Dall'Asta M, Del Rio D, Sgoifo A, van Sinderen D, Ventura M, Turroni F. (2017), How to Feed the Mammalian Gut Microbiota: Bacterial and Metabolic Modulation by Dietary Fibers. Frontiers in Microbiology  8: 1749.

Turroni, F., Milani, C., Duranti, S., Lugli, G.A., van Sinderen, D., and Ventura, M. (2018). B. bifidum PRL2010: scientific support of its use as an effective probiotic bacterium in the infant gut. Nutrafoods 17:173-178.
10.  Ferrario C, Lugli GA, Ossiprandi MC, Turroni F., Milani C, Duranti S, Mancabelli L, Mangifesta M, Alessandri G, van Sinderen D, Ventura M. (2017) Next generation sequencing-based multigene panel for high throughput detection of food-borne pathogens. Int J Food Microbiol. 256:20-29.


Main collaborations

International collaborations


·      Department of Microbiology, National University of Ireland, Cork Prof. D. van Sinderen

·      Institutos Lacteos delle Asturies, Spain Dr. A. Margolles

·      Department of Food Science, University of Massachusetts, USA Dr. D. Sela

·      Department of Food Sciences, University, Raleigh, North Carolina, USA Prof. R. Barrangou


Active projects

·      Italian Ministry of Health Grant (Bando Ricerca Finalizzata 2018, Linea Giovani Ricercatori). “Lung microbiota and related immunity role in predicting ventilator associated pneumonia (vap) development in mechanical ventilated patients” PI of University of Parma Unit: Prof.ssa F. Turroni.

Partecipants: Dott.ssa L. Alagna (coordinator, Ospedale Maggiore Policlinico, Milano), Dott. F. Magni (PI of Ospedale San Gerardo Monza e Brianza Unit).